Genetic Testing
Copper Oaks Goldendoodle puppy’s parents are tested to ensure they are negative for the following common genetic diseases
DM – Degenerative Myelopathy
DM is an adult onset neurologic condition with progressive limb weakness and muscle loss, usually seen to occur around middle age. There is thought to be other factors that play into exhibition of this disease. Dogs that carry two genes for DM (affected) are at risk, but may not be affected. Mode of Inheritance: Autosomal Recessive with Incomplete Penetrance. Severity: 4, a high degree of severity when the disease manifests as it generally causes a decreased quality of life and may also decrease the life expectancy.
PRA – Progressive Retinal Atrophy
PRA is a condition of the eye. PRA is a group of diseases that eventually lead to blindness. PRA affecting Goldendoodles is recessively inherited. Dogs adjust to their blindness quite well and there is no pain associated with this disease. Impact: low degree of severity. It has mild effects and generally does not pose any significant health concerns, or is easily managed. Inheritance: Autosomal Recessive. Result types: clear, affected, carrier. Severity: PRA’s have a moderate degree of severity, it is not a fatal disease, though it can decrease the quality of life.
vWD – Von Willebrand disease
vWD is an inherited bleeding disorder resulting from a lack or reduced level of a normal blood clotting protein called von Willebrand factor (vWF). Disease presentation varies from asymptomatic to spontaneous hemorrhaging and prolonged bleeding after injury, surgery, or giving birth. Age of onset varies with some dogs only becoming obvious “bleeders” later in life. Without medical intervention, uncontrolled bleeding can result in death.
HUU – Hyperuricosuria
HUU means elevated levels of uric acid in the urine. This trait predisposes dogs to form stones in their bladders or sometimes kidneys. These stones often must be removed surgically and can be difficult to treat. HUU is inherited as a simple autosomal recessive defect.
